Nephrocolic Fistula in a Compromised Urinary Tract : A Case Identified via Radioisotope Mercaotiacetyltriglycine (MAG3) Diuretic Renography

Authors

  • Hsin Yen Tan Department of Urology, Hospital Selayang, Selangor, Malaysia, 68100
  • Kavesha Karunakaran Department of Nuclear Medicine, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia, 50586
  • Nadiah Abd Razak Department of Nuclear Medicine, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia, 50586
  • Ahmad Zaid Zanial Department of Nuclear Medicine, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia, 50586
  • Charng Chee Toh Department of Urology, Hospital Selayang, Selangor, Malaysia, 68100

DOI:

https://doi.org/10.11594/bjurology.2026.007.01.1

Keywords:

emphysematous pyelonephritis, MAG3, nephrocolic fistula

Abstract

Introduction. Nephrocolic fistula is an abnormal communication between the kidney and colon. It is rare and the presentation may be atypical. Diagnosis is usually made using retrograde pyelograde, CT scan or barium enema.

Case. We present the case of a nephrocolic fistula detected on a radioisotope renography (MAG3) scan in a 74-year-old woman, who has a poorly controlled diabetes mellitus with a dysfunctional urinary tract due to recurrent emphysematous pyelonephritis (EPN) of the left kidney, complicated by a left ureteric stricture, pyonephrosis and neurogenic bladder secondary to diabetic cystopathy. She underwent multiple ureteric stentings, drainage procedures, and prolonged antimicrobial treatments for multidrug-resistant and fungal urosepsis. A renal MAG3 scan later revealed abnormal tracer accumulation in the descending colon, suggestive of a nephrocolic fistula. This case underscores the diagnostic challenges of nephrocolic fistula in individuals with a compromised urinary tract.

Conclusion. Urologists should maintain a high index of suspicion for nephrocolic fistula particularly in individuals with a compromised urinary tract. Alternative diagnostic imaging may be utilized to establish the diagnosis.

References

Jain T, Rastogi R, Aggarwal A, Khajuria L, Pratap V. Occurrence of retrorenal colon in the Indian population–a significant finding from urological perspective. Acta Med Int. 2023;10(2):109-11. doi: 10.4103/amit.amit_50_23

Wan Y, Xiao F, Wu J, Chen C. A case of nephrocolic fistula presenting primarily with changes in bowel habits. Urol Case Rep. 2025;58:102904. doi: 10.1016/j.eucr.2024.102904

Hillman E, Fu H, Anele U, Anele UA. Colo-renal fistula in a patient with refractory anemia and recurrent urinary tract infections: case report and review of the literature. Cureus. 2023;15(9):e44741. doi: 10.7759/cureus.44741

Nassani N, Villa E, Carroll RE. Use of an over-the-scope clip for closure of an iatrogenic nephrocolic fistula resulting from cryoablative therapy for renal cell cancer of a transplanted renal graft. ACG Case Rep J. 2021;8(4):e00559. doi: 10.14309/crj.0000000000000559

Kayarian FB, Dynia S, Timmermann AP, Lee J, Olaitan O. Ureterocolic fistula involving a native kidney and the sigmoid colon in a renal transplant recipient. Cureus. 2024;16(1):e52562. doi: 10.7759/cureus.52562

Patil SB, Patil GS, Kundaragi VS, Biradar AN. A case of xanthogranulomatous pyelonephritis with spontaneous renocolic fistula. Turk J Urol. 2013;39(2):122–5. doi: 10.5152/tud.2013.026

Correia DC, Antunes RM, Ferreira P. Nephroenteric fistula after lithotripsy: a rare complication. Int J Radiol Imaging Technol. 2019;5:048. doi: 10.23937/2572-3235.1510048

Petca RC, Salaheddin Y, Popescu RI, Mares C, Braticevici B, Petca A, et al. Colon perforations related to PCNL in a tertiary center: a retrospective study. Rom J Urol. 2019;18(4):34–9

Brandes ER, Pais VM Jr, Hartnett RD, Sternberg KM. AUA Update Series.

Öztürk H. Gastrointestinal system complications in percutaneous nephrolithotomy: a systematic review. J Endourol. 2014;28(11):1256–67. doi: 10.1089/end.2014.0344

Poyraz NY, Özdemir E, Keskin M, Türkölmez Ş. Additional value of SPECT/CT to Tc-99m MAG3 renal scintigraphy in the diagnosis of a patient with ureteroileal fistula. Mol Imaging Radionucl Ther. 2012;21(2):84–7. doi: 10.4274/Mirt.44

Draaisma J, Janssen M, Graafland N, Stommel M. Ureterocolic fistula detected by mercaptoacetyltriglycine (MAG-3) diuretic renography including SPECT–CT. BMJ Case Rep. 2019;12(9):e230559. doi: 10.1136/bcr-2019-230559

Published

2026-07-01

How to Cite

Tan, H. Y., Karunakaran, K., Abd Razak, N., Zanial, A. Z., & Toh, C. C. (2026). Nephrocolic Fistula in a Compromised Urinary Tract : A Case Identified via Radioisotope Mercaotiacetyltriglycine (MAG3) Diuretic Renography. Brawijaya Journal of Urology, 7(01), 1-5. https://doi.org/10.11594/bjurology.2026.007.01.1